Three topics of major interest for neursurgeons are covered in this volume of the Advances in Neurosurgery series, as the title suggests. First, neurosurgical standards of diagnosis and treatment are viewed from several points of view, including the legal one. Second, the many aspects of aneurysm surgery are dealt with: timing and grading, monitoring during the operation, postoperative vasospasm, Doppler sonography and new research in subarachnoid hemorrhage. Third, the diagnosis and treatment of malignant gliomas are discussed; there are preliminary reports on interstitial laser-assisted thermal therapy, immunotherapy and radiopharmaceutical substances as well as the standard forms of neurosurgical and radiation treatment.

InhaltsangabePresident's Opening Remarks.- Fedor Krause Memorial Lecture.- Neurosurgical Standards.- Neurosurgical Standards and Quality Assurance.- The Concept of Neurosurgical Standards from the Clinician's Perspective.- Medical Treatment Standards from a Legal Perspective.- Cerebral Aneurysms.- Endovascular Treatment of Berry Aneurysms by Endosaccular Occlusion.- Strategies of Endovascular Treatment of Large and Giant Intracranial Aneurysms.- Endovascular Treatment of Basilar Bifurcation Aneurysms.- Embolization of Large Aneurysms with Detachable Balloons.- Endovascular Treatment of Internal Carotid Artery Aneurysms.- Possibilities and Limitations of Endovascular Techniques for the Treatment of Craniocerebral Aneurysms.- Technical Possibilities and Aids in Treating Aneurysms in Open Surgery.- Surgical Procedure in Multiple Cerebral Aneurysms.- Circulatory Arrest and Hypothermia in the Treatment of Cerebral Aneurysms: Preliminary Results.- Principles of Aneurysm Surgery in the Acute Stage of Subarachnoid Hemorrhage.- Prognosis of Aneurysmal Subarachnoid Hemorrhage: Prospective Study on 543 Patients.- Early Versus Delayed Aneurysm Surgery in Subarachnoid Hemorrhage in Clinical Grade Hunt-Hess III.- Poor-Grade Patients with Aneurysmal Subarachnoid Hemorrhage: Early or Late Operation?.- Timing and Grading: Problems in Poor-Grade Subarachnoid Hemorrhage.- Early Operation in the Elderly?.- Management Results of a Series of Predominantly Delayed Operations and Ruptured Aneurysms.- Analysis of Relevant Intervals Between Subarachnoid Hemorrhage and Surgery on Patients with Aneurysm and Its Influence on the Decision for Early or Delayed Surgery.- Significance of the History for the Planning of Therapy After Subarachnoid Hemorrhage.- Microsurgical Strategy and Surgical Results in Carotid Ophthalmic Artery Aneurysms.- Surgery in Cases of Subarachnoid Hemorrhage Without Definite Angiographic Evidence of Vascular Malformation.- Differential Diagnostic Problems and Treatment of Thrombosed Giant Intracranial Aneurysms.- Cerebral Artery Aneurysm in Childhood: Surgical Indications and Results.- Multiple Intracranial Aneurysms: Considerations in Planning Surgical Management.- Psychological Stress During Operations of Aneurysms: A Factor in the Surgical Treatment of Aneurysms. Cardiac Output and Blood Pressure of the Surgeon.- Multimodal Monitoring of Evoked Potentials in Subarachnoid Hemorrhage Following a Ruptured Aneurysm.- Necessity of Control Angiography After Aneurysm Surgery.- Magnetic Resonance Angiography of Cerebral Artery Aneurysms: Present Capabilities and Limitations.- Differential Disturbances of Memory and Mood Following Striatum and Basal Forebrain Lesions in Patients with Ruptures of the Anterior Communicating Artery.- Treatment of Cerebral Vasospasm with Hypervolemia and Hypertension.- Value of Transcranial Doppler Sonography in Patients Treated with Nimodipine.- Correlation Between Cerebral Blood Flow Velocity in Basal Cerebral Arteries and Nimodipine Concentration in Serum and Plasma After Acute Subarachnoid Hemorrhage.- Laser Irradiation of Experimental Carotid Aneurysms: Long-term Results and Histological Alterations.- Effects of Intrathecal Thrombolysis on CSF Absorption After Experimental Subarachnoid Hemorrhage.- Malignant Gliomas.- The Neurosurgical Treatment of Malignant Gliomas.- Stereotactic Interstitial Brachycurietherapy (Iridium-192 and Iodine-125) in Nonresectable Low-Grade Gliomas.- Perspectives of Glioma Treatment with Boron Neutron Capture Therapy in Europe.- Clinical Investigations in Boron Neutron Capture Therapy (BNCT): Pharmacokinetic, Biodistribution, and Toxicity of Na2B12H11SH (BSH) in Patients with Malignant Glioma.- Laser-Induced Interstitial Thermotherapy of Malignant Gliomas.- Interstitial Laser-Assisted Thermal Therapy of Central Brain Tumors: Preliminary Report.- Transforming Growth Factors-? in Malignant Glioma: Preliminary Studies on Inhibition by Antisense Oligodeoxynucleotides.- Local Adjuvant Adoptive I